Sakthan Thampuran Palace in Thrissur once belonged to the Perumpadappu Swaroopam, the ruling dynasty of Kochi. This was the centre of power of King Rama Varma Sakthan Thampuran, who ruled Kochi between AD 1790 and 1805. His rule was regarded as the Golden Era of the Cochin dynasty.

The palace is close to the Vadakkumnathan temple in Thrissur. It was once known as Vadakkechira Kovilakam and it was the king who renovated it into the present form. The palace is built in a blended style of Kerala and the Dutch architecture. The palace keeps with it the historical remnants of some important events like the visit of Tipu Sultan with his army. The palace has a very old Sarpakavu (sacred serpent grove) in its premises. At present, there is a Heritage Garden which preserves the rare medicinal plants of Kerala.

The palace has been recently renovated by the State Archaeology Department with a few additions like Bronze Gallery, Sculpture Gallery and a Numismatics Gallery.