In Ayurveda, rejuvenation or Rasayana Chikitsa is the golden way to attain longevity and health. An elaborate description of this process of revitalization can be found in the classical texts. ‘Pancha’ means ‘five’ and ‘Karma’- ‘action’. The five fold therapy is aimed at Shodhana, the eradication of the basic cause of disease. Shodhana along with Shamana, the mitigation of the disease and its symptoms, are the two concepts of disease management in Ayurveda.